Microbiology & Immunology Publications
Title
Micronutrient supplemented probiotic yogurt for HIV-infected adults taking HAART in London, Canada
Document Type
Article
Publication Date
9-1-2000
Journal
FEMS Microbiology Letters
Volume
190
Issue
1
First Page
177
Last Page
180
URL with Digital Object Identifier
10.1016/S0378-1097(00)00331-1
Abstract
Lactobacilli have been shown to be important in the maintenance of the healthy urogenital flora. One strain, Lactobacillus fermentum RC-14, releases surface-active components which can inhibit adhesion of uropathogenic bacteria. Using a quantitative method for determining inhibition of adhesion, a protein with high anti-adhesive properties against Enterococcus faecalis 1131 was purified. The N-terminal sequence of the 29-kDa protein was identical to that of a collagen-binding protein from Lactobacillus reuteri NCIB 11951, and exhibited close homology with a basic surface protein from L. fermentum BR11. The results suggest that this anti-adhesive cell surface protein of Lactobacillus could protect against uropathogens by preventing their adhesion. (C) 2000 Published by Elsevier Science B.V.