Electronic Thesis and Dissertation Repository

Degree

Master of Science

Program

Surgery

Supervisor

Doherty, Christopher

2nd Supervisor

Sarma, Sisira

Co-Supervisor

Abstract

Breast reconstruction following mastectomy is increasing and implant-based breast reconstruction is the most common surgical approach. Saline and silicone implants have different cost and complication profiles and it is unclear which is the more cost-effective option. A systematic review of the literature was undertaken to summarize the quality of life data in breast reconstruction, specifically, previously published health state utility values relevant to breast reconstruction. In addition, a cost-utility analysis was undertaken from the perspective of the third-party payer, accounting for the most common complications associated with saline and silicone implants. This demonstrated that despite the increased initial cost of silicone implants, they are cost-effective with a willingness-to-pay threshold of $50,000 (ICUR $52.26/QALY). Overall, silicone implants provide improved quality of life with a marginal cost increase.

Available for download on Friday, January 31, 2020

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