Electronic Thesis and Dissertation Repository


Master of Science


Health and Rehabilitation Sciences


Trevor Birmingham




Objectives: 1) Estimate test-retest reliability of knee angles and moments during gait in patients with knee osteoarthritis (OA) using the Gait Real-Time Analysis Interactive Lab (GRAIL); 2) Examine concurrent validity of knee angles and moments using the GRAIL and overground system (gold standard); and 3) Examine known-groups validity of knee angles and moments in patients with knee OA and healthy ontrols.

Methods: Patients and controls walked using both systems to produce knee angle and moment waveforms during stance, enabling discrete measure comparisons. atients completed a second session within one week.

Results: Intraclass correlation coefficients ranged from 0.52-to-0.93 for test-retest reliability. Pearson correlations ranged from 0.05-to-0.96 with transverse plane peaks being weakest. Patients had significantly higher first peak knee adduction moments than controls (0.58 %BW*ht).

Conclusion: Preliminary results suggest adequate reliability and validity of knee angles and moments in patients using the GRAIL. Knee transverse plane measures should be interpreted cautiously.

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