Electronic Thesis and Dissertation Repository


Master of Science




Dr. Michelle Mottola


One purpose was to identify the need for specialized care (My Clinic) for women with a pre-pregnancy body mass index (BMI) of ≥ 35 kg/m2.. Women receiving My Clinic care were compared to a matched cohort control group (perinatal database, N=47). My Clinic care significantly reduced rates of macrosomia (5% vs 28%, p=0.02) and small birth weight babies (0% vs 6%, p=0.00) compared to perinatal database.

The second purpose was to test the efficacy of a Nutrition and Exercise Lifestyle Intervention Program (NELIP) in this clinical setting to prevent excessive weight gain, macrosmia, small birth weight babies and pregnancy complications. Twelve women with a BMI ≥ 35 kg/m2 were randomized between 12-20 weeks of pregnancy to Nutrition-only, Exercise-only, or full NELIP. Exercise-only intervention reduced rate of weight gain (0.15 ± 0.13 kg/week vs 0.61 ± 0.12 kg/week, p=0.01) compared to Nutrition-only. Combining a nutrition and exercise intervention appeared difficult for this population, as 100% of the women randomized to full NELIP did not complete the program.