Date of Award
2006
Degree Type
Thesis
Degree Name
Master of Science
Program
Biology
Supervisor
Dr. John Steele
Abstract
This study demonstrates that hypertrehalosemic hormone-II (Peram-HTH-II) stimulates carbohydrate and lipid metabolism in the American cockroach, Periplaneta americana. The hypertrehalosemic and hypolipemic effect of HTH-II in hemolymph was shown to be dose- and time-dependant. The low dose of HTH-II required to produce these effects is less than that known to be contained in the corpus cardiacum, and as such could be representative of the amount of hormone naturally released into the blood of the insect. The duration of the effect of HTH-II was shown to be comparable for both carbohydrate and lipid metabolism, suggesting that both events may be required to produce the full physiological effect of HTH in the cockroach. Low doses of HTH-II were also shown in this study to stimulate an increase in the movement of free fatty acids from hemolymph to fat body where they are incorporated into newly synthesized triacylglycerol.
Recommended Citation
Michitsch, Julia-Lynn, "EVIDENCE FOR THE PHYSIOLOGICAL REGULATION OF CARBOHYDRATE AND LIPID METABOLISM BY Peram-HTH-II IN THE COCKROACH (Periplaneta americana)" (2006). Digitized Theses. 5080.
https://ir.lib.uwo.ca/digitizedtheses/5080