Date of Award
Master of Science
Dr. Kevin Willits
Dr. Dianne Bryant
The purpose of this study was to investigate isokinetic strength, quality of life, range of motion, and calf circumference for patients with acute Achilles tendon rupture treated non- operatively with accelerated functional rehabilitation with or without Autologous Conditioned Plasma (ACP®).
We used a cohort of patients (n=34) from a published randomized trial to serve as our historical control group. We recruited 51 consecutive patients and administered two ACP® injections during the first four weeks post injury.
The mean between groups difference in plantar flexion strength (injured/uninjured) at one year post injury was 2.9% (95% Cl -13.6 to 7.8), p = 0.6 and -0.3% (95% Cl -13.6 to 13.0), p = 1.0 at 30°/s and 607s respectively. All secondary outcomes were also not different.
The addition of ACP to a non-operative treatment protocol with accelerated functional rehabilitation does not provide better outcomes at one year post Achilles tendon rupture.
Kaniki, Nicole Lynn, "A Prospective Cohort Study with Historical Control to Determine the Effectiveness of Autologous Conditioned Plasma (ACP®) in the Non-operative Treatment of Acute Achilles Tendon Ruptures" (2011). Digitized Theses. 3247.