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Description
A targeted catalase, packaged and delivered via exosomes intranasally, provides protection for cochlear cells against oxidative stress, the kind of stress that results from loud noise exposure. It is able to cross the blood-brain barrier and does not result in negative outcomes elsewhere in the body.
Publication Date
2018
Publisher
BrainsCAN
City
London
Keywords
Hearing and auditory perception
Disciplines
Neurosciences
Notes
Western Faculty, Group or Institution
Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry
Associated project summary
Development of a novel pharmaceutical to prevent noise-induced hearing loss
(Available in Scholarship @ Western)