A dynamic neonatal heart phantom for ultrafast color Doppler echocardiography evaluation
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
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© 2019 SPIE. New high-frame-rate ultrasound imaging techniques are being developed to image tissue motion and blood flow with high sensitivity and at high temporal resolution. An emerging application for these new techniques is diagnosing inutero and neonatal cardiac disease. We have developed a morphologically and hemodynamically accurate neonatal heart phantom to provide a high-fidelity physical model for laboratory testing of ultrafast color Doppler echocardiography methods. This paper summarizes the design and functionality of the simulator by measuring pressure gradients across the mitral valve at a physiologic heart-rate range and stroke volume and by evaluating valve function using 2D transesophageal echocardiography (TEE) and Doppler images. The phantom achieved normal physiological pressures across the mitral valve ranging from 42 to 87 mmHg in systole and 2.4 to 4.2 mmHg in diastole at heartrates of 100, 125 and 150 beats per minute (bpm), with a realistic neonatal stroke volume of 7 ml. 2D ultrasound images were obtained at 60 bpm.