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Theses/Dissertations from 2017

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Maternal Nutrient Restriction in Pregnant Guinea Pigs and the Impact on Fetal Growth and Brain Development, Andrew Ghaly

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Synaptic Mechanisms for the Hypothalamic-Pituitary-Adrenal Axis Activation by Prostaglandin E2, Zahra Khazaeipool

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Alternative splicing and extra-telomeric role of telomerase reverse transcriptase isoforms in human embryonic stem cells, Joohwan Kim

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The Role of OATP-Mediated Statin Transport in Pancreatic Beta Cell Function, Michelle S. Kim

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The Role of p62/SQSTM1 in TGFβ-dependent EMT and Autophagy, Evelyn Ng

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Investigating The Acute Levodopa Response In Early To Advanced Parkinson’s Disease, Marcus M. Pieterman

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The Loss Of ATRX Creates Susceptibility To KRAS-Mediated Pancreatic Damage, Claire C. Young

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S-Nitrosylation Suppresses Stromal Interaction Molecule-1 Activation and Ameliorates Cardiomyocyte Hypertrophy, Jinhui Zhu

Theses/Dissertations from 2016

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Glycosylation on Stromal Interaction Molecule-1 Ca2+ sensing region enhances Store Operated Ca2+ Entry, Yoo Jung Choi

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New Insights into Signal Detection of the Effects of Exposures during Pregnancy, Fatma Etwel

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PDZ Protein Regulation of β-arrestin Recruitment and GPCR Trafficking, Sarah Gupta

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CAL and MAGI PDZ Protein Regulation of CRFR1 and 5-HT2AR Trafficking and Signaling, Maha Mahmoud Hammad

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The Effect of AST-120 on Hepatic Metabolism and Transport in Chronic Kidney Disease, Andrew S. Kucey

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The Mitochondrial Calcium Uniporter Is Autoregulated by Cation Binding to the β-Grasp-Like Matrix Domain, Samuel K. Lee

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Evaluating the role of intestinal transporters in fruit juice-drug interactions, Mandy MJ Li

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Evaluation of Food Effects on the Oral Pharmacokinetics of Rosuvastatin, Cheynne C. McLean

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The Biophysical Alterations to Pulmonary Surfactant during Lung Injury, Scott D. Milos

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Identification Of A Novel Interaction Between Integrin-Linked Kinase And Beta-Arrestin 1, Hannah E. Murphy-Marshman

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Corticotropin releasing factor receptor type 1 signaling in epilepsy and traumatic brain injury, V V Chakravarthi Narla

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Maternal Nutrient Restriction with Fetal Growth Restriction in Guinea Pigs Impacts Brain Development and Neuroimaging Correlates in Neonatal Offspring, Catherine Nevin

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The Role of GABA Signalling in Lung Macrophage Immune Response, Jacob W. Poirier

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Insights into the role of connexin26 and connexin30 in skin health, syndromic disease, and cutaneous wound healing, Eric R. Press

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Pharmacogenetics of Non-Motor Symptoms in Parkinson's Disease, Brian Robertson

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Putative Pore-lining Residues and Intracellular Magnesium Influence Connexin50 Unitary Gap Junction Channel Conductance, Swathy Sudhakar

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Beta blocker dialyzability and effectiveness in chronic hemodialysis patients, Alvin Tieu

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Signal Transduction Mechanisms Mediating the Regulation of Vascular G Protein-Coupled Receptors, Elena Tutunea-Fatan

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A Non-Canonical Role for Choline Acetyltransferase in Chromatin Organization and the Response to Beta-Amyloid, Warren R. Winick-Ng

Theses/Dissertations from 2015

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Septic Murine Pulmonary Microvascular Endothelial Cell Barrier Dysfunction is Regulated by Tissue Inhibitor of Metalloproteinases 3, Valerie Arpino

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KISS1R Signaling Promotes Breast Cancer Drug Resistance, Alexandra J. Blake

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Studies into the Regulation of FTO by Angiotensin II in Cardiomyocyte Hypertrophy, Kwame N. Boakye-Ansah

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Atrial Fibrillation Promotion by Intermittent Hypoxia in the Rat, Sara Bober

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TIMP3 Regulation of Macrophage Activation and Apoptosis, Michael S. Brock

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Non-Invasive Determination of Pre-Clinical Markers of Cardiovascular Diseases in Low Birth Weight and Maternal Western Diet Guinea Pig Offspring Exposed to a Postnatal Western Diet, Jacky Chiu

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The Rho GTPases Rac1, Cdc42, and RhoA Regulate APP Transport to Lysosomes and Aβ Production, Justin K. Chiu .

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Cardioprotective Role of the Cholinergic System, Mouhamed Dakroub

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Skeletal Muscle Lipid Metabolism and Markers of Insulin Resistance in Young Male Low Birth Weight Offspring in Combination With a Postnatal Western Diet, Kristyn Pamela Dunlop

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Maternal Nutrient Restriction in Pregnant Guinea Pigs Impacts Fetal-Placental Growth and Oxygenation, Alexander Elias

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Inhibition of elongation factor 1A-1 activity and hepatic lipotoxicity, Alexandra Margaret Anne Hetherington

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Engineered connexin40 variants increased docking and function of heterotypic connexin40/connexin43 gap junction channels, Arjewan Jassim

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Modulation of synaptic plasticity by hippocampal theta rhythm, Clayton Law

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Cardiomyocyte Polarity and Embryonic Heart Development: Role of Rac1, Carmen Leung

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Fibulin-3 Promotes Triple Negative Breast Cancer Cell Invasion, Michelle M. Noonan

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The CTCF Chromatin Organizer is Required for Hindlimb Development, Katherine L. Rabicki

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The Role of Connexins and Pannexins in Mammary Gland Development and Tumorigenesis, Michael K. G. Stewart

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Stability and Activity of Naturally Occurring RGS2 Variants, Patrick Stockwell

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The Role of Shroom3 in Kidney Development, Alexandra Sull

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Novel Video Imaging to Examine Cardiac Function in Xenopus Embryos, Judith Sull

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Pathophysiologic Mechanisms of Immune-mediated Drug Hypersensitivity Reactions to Sulfonamides, Elham A. Sultan

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Mechanisms of ATF4-mediated neuronal apoptosis, Patrick Swan

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Intracellular Trafficking Governs the Processing of the Amyloid Precursor Protein and the Secretion of Beta-Amyloid, Joshua Hoi Ki Tam

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Investigating The Mechanism Of Ectopic Mineralization In A Mouse Model Of Diffuse Idiopathic Skeletal Hyperostosis (DISH), Neil A. Tenn

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Investigating the Fibroblastic Origin of Skin-Derived Precursors and the Role Of CCN2 as a Mediator of Myofibroblastic Differentiation, Matthew Tsang

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Role of RGS2 in Cellular Stress, Chang-Hui Wang

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Characterization of the nicotine-induced endoplasmic reticulum stress response in the rat placenta in vivo and in vitro, Michael Ka Chun Wong

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Cytochrome P450 3A4 Expression and Regulation in Non-Alcoholic Fatty Liver Disease, Sarah J. Woolsey

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Regulation of Leukocyte-Derived Matrix Metalloproteinases and Azurophilic Enzymes in Human Diabetic Ketoacidosis, Martin Woo

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Function Study of Atrial Fibrillation-Linked Connexin Mutants and Heterotypic Docking Compatibility of Cardiac Connexins, Willy G. Ye

Theses/Dissertations from 2014

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Modulation of the Cardiomyocyte Hypertrophic Responses to Endothelin-1 by Adipocytes, Suresh Chandra Bairwa

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Pancreatic Beta Cell Plasticity and Involvement of Insulin-Expressing Progenitor Cells, Christine A. Beamish

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Characterization of ALDH Positive Cells in the Human Fetal Pancreas, Amanda Oakie

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Role of Integrin-linked kinase in epidermal integrity and barrier function, Samar Sayedyahossein