Pathology Theses and Dissertations

 

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Theses/Dissertations from 2017

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Immunological Impact of CLI-095 on Dendritic Cell Maturation and Hypoxia-re-oxygenation induced inflammatory injury, Hajed Obaid Alharbi

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ERK5 Expression in Brain Tumours, Reem Ansari

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Expression of Human Tissue Kallikreins (KLKs) in Polymorphous Low Grade Adenocarcinoma (PLGA), Jacqueline M. Cox

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A Clinico-Pathological Study of the Structural and Functional Changes in the Retina and Optic Nerve Following Diabetic Retinopathy Treatments, Richard Filek

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Mechanisms underlying chemotherapy-induced vascular proliferation in ovarian cancer, Zeynep Gülsüm Kahramanoğlu

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The Effect of Glucocorticosteroids on Th2 cells, Tharsan Kanagalingam

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Hsp90 and its Co-chaperones Modify TDP-43 Localization, Aggregation, and Toxicity, Lilian T. Lin

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Characterization of Hemangioma-initiating Stem Cells, Natalie Montwill

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Postnatal β1 Integrin Deficiency in Pancreatic Beta-Cells Impairs Function and Survival, Jason E. Peart

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Up-regulation of junctophilin-2 prevents ER stress and apoptosis in hypoxia/reoxygenation-stimulated H9c2 cells, Zijun Su

Theses/Dissertations from 2016

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Body and Organ Measurements in Infants and Neonates: An Autopsy Study, Audrey-Ann M. Evetts

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The Long Non-coding RNA Malat1 Regulates Inflammatory Cytokine Production in Chronic Diabetic Complications, Andrew D. Gordon

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Expression of Kallikrein-Related Peptidases (KLKs) in Adenoid Cystic Carcinoma, Zachary R. Kerr

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Mechanisms regulating stem cell phenotype in infantile hemangioma, Niamh Richmond

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Etiology of Motor Vehicle Collision Fatalities in Urban and Rural Canada, James R. Roos

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Identification of a Nuclear Localization Signal (NLS) within the Pleckstrin Homology (PH) domain of Rho Guanine Nucleotide Exchange Factor (RGNEF), Michael V. Tavolieri

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Development and Performance Evaluation of an Antibody-Based Technology for Detection of E. coli O157 in Meat Samples and Its Potential Evolution Using Antibody Engineering, Yadira Tejeda Saldaña

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Regulation of Phosphatase and Tensin Homolog Expression and Activity by Transforming Growth-Factor Beta in the Trabecular Meshwork Cells: Implications for Primary Open Angle Glaucoma, Nikoleta Tellios

Theses/Dissertations from 2015

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Phase II Clinical Trial of Concurrent Neoadjuvant Chemotherapy With Radiotherapy in Locally Advanced Breast Cancer, Muriel Brackstone

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Expression Of Human Kallikrein Protein And mRNA In Maxillofacial Cysts And Tumours, Karl Kevin Cuddy

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Chromatin Structure and Differential Accessibility of Homologous Human Mitotic Metaphase Chromosomes, Wahab A. Khan

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β-adrenergic receptor-dependent and -independent effects of propranolol in infantile hemangioma, Jina J.Y. Kum

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CD4+ T-cell Mediated Microvascular Endothelial Cell Death and Chronic Cardiac Allograft Rejection Involves Necroptosis, Cecilia YT Kwok

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Epithelial to mesenchymal transition in the metastatic progression of gastroenteropancreatic neuroendocrine tumours, Stephanie Mok

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Protective Effect of Modified Human Fibroblast Growth Factor on Diabetic Nephropathy, Ana M. Pena Diaz

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Diabetic Bone Marrow & Stem Cell Dysfunction, Meghan A. Piccinin

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Investigation of Pancreatic β-Cell Insulin Receptor Regulation of β-Cell Growth, Function, and Survival Via a Temporal Conditional Knockout, Liangyi Zhou

Theses/Dissertations from 2014

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The Role Of The RNA-Binding Protein Rho Guanine Nucleotide Exchange Factor In The Cellular Stress Response, Kevin WH Cheung

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Exposure to Environmental Contaminants and Stress as Determinants of Health in Three Communities: Walpole Island and Attawapiskat First Nations and Naivasha, Kenya, Deirdre Phaedra Henley

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miRNA Regulation of Programmed Cell Death-1 in T Cells: Potential Prognostic and Therapeutic Markers in Melanoma, Nathan J. Johnston

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Cell Death Regulates Injury and Inflammation During Renal Allograft Transplantation, Arthur Lau

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Role of SIRT1 in Vascular Complications of Diabetes, Rokhsana Mortuza

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RIPK3 Regulates Microvascular Endothelial Cell Necroptosis and Cardiac Allograft Rejection, Alexander William Pavlosky

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The Role of Integrins in Support of Pancreatic Function, Survival and Maturation, Matthew Riopel

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Polycomb Repressive Complex 2 Regulates miR-200b in Retinal Endothelial Cells: Possible Implications in Diabetic Retinopathy, Michael A. Ruiz

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Association of Head and Cervical Injuries in Pediatric Occupants Involved in Motor Vehicle Collisions, Shayan Shekari

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Development of Non-Covalent Functionalization of Carbon Nanotubes for siRNA Delivery, King Sun Siu

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The Expression and Potential Significance of Human Kallikreins 6, 7, 8, 10, 13, and 14 in the Epithelium of Selected Odontogenic Cysts and Tumors of Variably Aggressive Biological Behaviour, Rebecca Woodford

Theses/Dissertations from 2013

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Targeted siRNA Delivery Methods for RNAi-Based Therapies, Di Chen

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Elucidating the Role of Menin During Islet Cell Development in the Human Fetal Pancreas, Jessica L. Dubrick

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Vascular Stem Cells in Diabetic Complications, Emily C. Keats

Theses/Dissertations from 2012

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Immunohistochemical Studies of Expression and Correlation of Osteopontin, CD44, and Integrin αVβ3 in Selected Benign and Malignant Salivary Gland Tumours, Tommy Fok

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The role of non-canonical Wnt/planar cell polarity signalling in breast cancer progression, Connor D. MacMillan

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Elucidating the Function of Transplanted Islets of Langerhans and Predicting Their Ability to Reverse Diabetes, Andrew R. Pepper

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Role of ERK5 in Diabetic Vascular Complications, Yuexiu Wu

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Regulation of NK cell-mediated tubular epithelial cell death and kidney ischemia-reperfusion injury by the NKR-P1B receptor and Clr-b, James Yip

Theses/Dissertations from 2011

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A Model System for Rapid Identification and Functional Testing of Genes Involved in Early Breast Cancer Progression, Lesley H. Souter