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Theses/Dissertations from 2017

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Evaluating Evolving Leukocyte Populations In Peripheral Blood Circulation Post-Concussion In A Human Longitudinal Analysis Of Female Athletes, Kevin A. Blackney

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Discovery of Novel Diagnostic Biomarkers on Prostate Tumor Microparticles for Discriminating Between Low and High Risk Prostate Cancer and Improving Prostate Cancer Screening, Sabine Brett

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Characterizing Ferroportin Trafficking in Macrophages During Phagocytosis, Tayler J. Farrell

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Rapid Regulatory and Effector Immune Responses in Toxic Shock Syndrome, Peter Anthony Szabo

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Superantigen responsive T cells are required for nasopharyngeal infection by Streptococcus pyogenes, Joseph J. Zeppa

Theses/Dissertations from 2016

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Structural and functional studies of the heptose modifying enzymes that play a role in Campylobacter jejuni virulence., Heba Soliman Barnawi

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Evolutionary History and Biological Regulation of CD93, Jack W D Blackburn

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Iron acquisition strategies employed by Staphylococcus lugdunensis, Jeremy R. Brozyna

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Evaluation of MERTK evolution and efferocytosis signalling, Amanda L. Evans

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Protective Benefits of Hydrogen Sulfide Treatment During Renal Transplantation, Ian Lobb

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Utilizing untargeted metabolomics to characterize microbial communities and identify biomarkers of an unhealthy state, Amy McMillan

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Mitigation of Pesticide Toxicity by Food-Grade Lactobacilli, Mark E. Trinder

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Characterization of microbial communities in the mammary glands and the influence of this microbiota on health and disease, Camilla Urbaniak

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At the interface of glycolipids and glycoproteins in the two gastro-intestinal pathogens Campylobacter jejuni and Helicobacter pylori, Najwa Zebian

Theses/Dissertations from 2015

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Recombinase-based in vivo expression technology identifies a Streptococcus pyogenes bacteriocin important for niche adaptation in the nasopharynx, Brent D. Armstrong

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Clinical and Mechanistic Insights into Novel Probiotic Functions and Formulations, Jordan Bisanz

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Characterizing the C-terminal Region of Human Adenovirus E1A: An Undiscovered Country, Michael J. Cohen

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A Novel Murine Myelin Oligodendrocyte Glycoprotein Fusion Protein, MOGtag, Induces Appropriate Autoimmune B Cell Germinal Center Responses And Central Nervous System Autoimmune Disease, Amy K. Dang

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Genomic analyses of Paenibacillus polymyxa CR1, a bacterium with potential applications in biomass degradation and biofuel production, Alexander W. Eastman

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Supplementation With Hydrogen Sulfide Helps Mitigate The Effects Of Ischemia Reperfusion Injury In A Model Of Donation After Cardiac Death Renal Transplantation, Jaskirandeep Kaur Grewal

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Kidney Injury Molecule-1 Signalling in Ischemic Acute Kidney Injury and Phagocytosis, Ola Z. Ismail

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Characterization of the AtsR/AtsT global regulatory pathway in Burkholderia ceocepacia, Maryam Khodai-Kalaki

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The E26 Transformation-Specific Transcription Factors PU.1, Spi-B, and Spi-C Regulate Transcriptional Activation and Repression of Nfkb1 to Control B Cell Development and Function, Stephen Ka Ho Li

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Characterization of fatty acid resistant Staphylococcus aureus mutants containing SNPs in cvfA, Melissa N. Loyzer

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The Role of Streptococcus salivarius as a Modulator of Homeostasis in the Oral Cavity, Kyle W. MacDonald

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Granulocyte colony-stimulating factor: Its role in gut-homing macrophage generation and colitis, and production by probiotics, Shahab Meshkibaf

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Development of a Novel Humanized Single Chain Antibody-Streptococcal Superantigen-Derived Immunotherapy Targeting the 5T4 Oncofetal Antigen, Kelcey G. Patterson

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Elucidating the Role of HDAC8 in Anthrax Lethal Toxin-Induced Pyroptosis and Cytokine Gene Silencing in Macrophages, Chantelle M. Reid

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Overcoming Innate and Acquired Therapy Resistance by Targeting DNA Repair in Human Cancer Cells, Mateusz Rytelewski

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Investigating The Regulation Of A Fatty Acid Efflux Pump In Methicillin Resistant Staphylococcus Aureus, James ET Schneider

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Iron Acquisition Mechanisms and Their Role in Staphylococcus aureus Survival and Virulence, Jessica R. Sheldon

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Contribution of enhanced intrinsic apoptosis to renal ischemia reperfusion injury in the absence of RIPK3 and Caspase-8 dependent regulated cell death, Ron Sung

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Streptococcus pyogenes Superantigens: Studies Into Host Specificity and Functional Redundancy, Adrienne T. Wakabayashi

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Molecular Characterization of HERC5: A Novel Multifunctional Antiviral Protein, Matthew W. Woods

Theses/Dissertations from 2014

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Transcriptional regulation of peptidylarginine deiminase type IV: implications for rheumatoid arthritis, Ali Abbas

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Analysis of Invariant Natural Killer T Cells in Intra-Abdominal Sepsis, Ram Venkatesh Anantha

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Elucidating the Signalling Pathway of Mer Tyrosine Kinase Receptor in Efferocytosis, Ekenedelichukwu Azu

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Cell Biology of the Entry of Bdellovibrio and Like Organisms, Ryan M. Chanyi

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siRNA Targeting of Thymidylate Synthase, Thymidine Kinase 1 and Thymidine Kinase 2 as an Anticancer Therapy: A Combinatorial RNAi Approach, Christine Di Cresce

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Chemical Communication of Antibiotic Resistance by Highly Resistant Bacteria., Omar M. El-Halfawy

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The Effect of Nutrition on the Microbiome in Pregnant Women and the Use of Micronutrient Supplemented Probiotic Yogurt to Improve Outcomes, Megan Kathleen Enos

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Probiotic therapy for heart failure: Investigating the potential anti-hypertrophic properties of probiotics, Grace L. Ettinger

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Sub-Inhibitory Antibiotics Enhance Virulence, Persistence, and Pathogenesis of Uropathogens, Lee W. Goneau

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Evolutionary and in silico analysis of the antiviral TRIM22 gene, Jenna Kelly

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Characterization of Efferosome Maturation and the Processing of Apoptotic Bodies, Yohan Kim

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HcpE, a potential immuno-modulatory protein from Helicobacter pylori that is dependent on the Disulfide bond protein DsbHP, Jeff Lester

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Indoleamine 2,3-dioxygenase confers resistance to chemotherapy and γ radiation to cancer cells, independent of direct immune involvement, Saman Maleki Vareki

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The Role of KIM-1 Mediated Efferocytosis by Cancer Cells in Blocking the Immunogenicity of Tumor Cell Death, Sahra Nathoo

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Role of peptidoglycan modifications in predation by Bdellovibrio bacteriovorus 109J, Diane C. Szmiett

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The role of superantigens during Staphylococcus aureus nasal colonization and infection, Stacey Xu

Theses/Dissertations from 2013

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The role of IL-22 produced by Th17 cells in Type 1 Diabetes, Stacey M. Bellemore

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Elucidating the role of cathepsin B in the lifecycle of influenza A virus, Macon D. Coleman

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Human Adenovirus E1A binds and retasks cellular hBre1, blocking interferon signalling and activating virus early gene transcription, Gregory J. Fonseca

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Structure-Function Analysis of UDP-Sugar: Polyisoprenyl Phosphate Sugar-1-Phosphate Transferases, Sarah E. Furlong

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Evaluating the Co-commensal Lifestyles of Staphylococcus aureus and Staphylococcus epidermidis, Piraveina Gnanasuntharam

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Cellular Adaptation of Macrophages to Anthrax Lethal Toxin-Induced Pyroptosis via Epigenetic Mechanisms, Chae Young Han

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The Interaction of the Human Adenovirus E1A Protein with the Human DREF Transcription Factor, Kris M. James

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Systematic Assessment of the Contribution of Superantigens to Nasopharyngeal Colonization in a Mouse Model of Streptococcal Infection, Katherine J. Kasper

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PEGylation as a novel tool to investigate the topology of Escherichia coli WecA, a membrane enzyme involved in lipopolysaccharide O antigen initiation, Stéphanie L. Lamothe

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Role of branched-chain amino acid transporters in Staphylococcus aureus virulence, Sameha Omer

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Systematic Analysis of Residues in Conserved Region 3 of the Human Papillomavirus 16 E7 Oncoprotein, Biljana Todorovic

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The Role of PU.1 and Spi-B in B Cell Acute Lymphoblastic Leukemia, Shereen Turkistany

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Characterization of Staphylococcus aureus Lipase, Vithooshan Vijayakumaran

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Folate Receptor-Targeting Liposomes for the Delivery of Antisense Molecules to Cancer Cells, Colin J. Way

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Gene Repression and Cell Cycle Regulation by PU.1 in Acute Myeloid Leukemia, Rachel GH Ziliotto

Theses/Dissertations from 2012

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Staphylococcus aureus response to long chain antimicrobial fatty acids, Benjamin Arsic

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Characterization of SLP-2 function in T lymphocytes, Darah Christie

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Role of IL-10 in the Immune Response to Staphylococcus aureus Nasal Carriage, Teresa Fernandez Plaza

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Restriction of HIV-1 replication by unique TRIM22 isoforms., Clayton Hattlmann

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Modulatory Effects Of North American Ginseng Extracts On Human Innate and Adaptive Immune Responses, Holly Rebecca Lemmon

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Sequesteration of lead, cadmium and arsenic by Lactobacillus species and detoxication potential, Marc A. Monachese

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The role of cystic fibrosis conductance regulator in the clearance of Burkholderia cenocepacia by macrophages, Hanna Ostapska

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Immune Responses to Homocitrullinated Protein/Peptide in Rheumatoid Arthritis, Mathias J. Scinocca

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The effect of dendritic cell mobilization on CD8+ T cell responses to influenza A virus, Adil N. Shivji

Theses/Dissertations from 2011

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Transactivation by human Adenovirus Early Region 1A-Conserved Region Three, Jailal NG Ablack

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The HIV-1 Tat Protein and Adverse Drug Reactions: A model system utilizing Jurkat T cells and sulphamethoxazole-hydroxylamine, Kaothara Adeyanju

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Serum iron uptake and virulence in Staphylococcus aureus, Federico C. Beasley

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The Role of Granulocyte Colony-Stimulating Factor in the Intestinal Immune System and the Response to Probiotics, Andrew J. Martins

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Critical Stages in Viral Replication - Entry, Gene Regulation and Egress, Matthew S. Miller

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Structure-Function Analysis of Enzymes of the Polyisoprenyl-Phosphate Hexose-1-Phosphate Transferase family, Kinnari B. Patel

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The intracellular behaviour of Burkholderia cenocepacia in murine macrophages, Jennifer S. Tolman