Department of Medicine Publications

 

As the largest department within the Schulich School of Medicine and Dentistry, the Department of Medicine hosts a vast range of research in its divisions. Research areas include cardiology, clinical immunology and allergy, clinical pharmacology, dermatology, critical care and emergency medicine, endocrinology and metabolism, gastroenterology, hematology, molecular toxicology, nephrology, respirology, and rheumatology.

Visit the Department of medicine website for additional information.

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Submissions from 2016

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Appropriate management of asymptomatic carotid stenosis, J. David Spence, Hongsong Song, and Guanliang Cheng

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Effect of renal impairment on atherosclerosis: Only partially mediated by homocysteine, J. David Spence, Bradley L. Urquhart, and Heejung Bang

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Taking care of volunteers in a stroke trial: A new assisted-management strategy, Amber C. Stuart, Jason J. Sico, Catherine M. Viscoli, Ashis H. Tayal, Silvio E. Inzucchi, Gary A. Ford, Karen L. Furie, Robert Cote, J. David Spence, David Tanne, and Walter N. Kernan

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Folic acid supplementation and chronic kidney disease progression, Christina M. Wyatt and J. David Spence

Submissions from 2015

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iStent as a Solo Procedure for Glaucoma Patients: A Systematic Review and Meta-Analysis, Monali S. Malvankar-Mehta, Yufeng Nancy Chen, Yiannis Iordanous, Wan Wendy Wang, John Costella, and Cindy M. L. Hutnik

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Immediate versus Delayed Sequential Bilateral Cataract Surgery: A Systematic Review and Meta-Analysis, Monali S. Malvankar-Mehta, Yufeng Nancy Chen, Sangita Patel, Angela Pui-Kei Leung, Man Mohan Merchea, and William G. Hodge

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Management of resistant hypertension, J. David Spence

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Statins and cataracts: Reverse causality?, J. David Spence

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Risk of stroke at the time of carotid occlusion, Catherine Yang, Chrysi Bogiatzi, and J. David Spence

Submissions from 2014

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SPARKLE (Subtypes of ischaemic stroke classification system), Incorporating measurement of carotid plaque burden: A new validated tool for the classification of ischemic stroke subtypes, Chrysi Bogiatzi, Thapat Wannarong, A. Ian McLeod, Marnin Heisel, Daniel Hackam, and J. David Spence

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Effects of homocysteine lowering with B vitamins on cognitive aging: Meta-analysis of 11 trials with cognitive data on 22,000 individuals, Robert Clarke, Derrick Bennett, Sarah Parish, Sarah Lewington, Murray Skeaff, Simone J.P.M. Eussen, Catharina Lewerin, David J. Stott, Jane Armitage, Graeme J. Hankey, Eva Lonn, J. David Spence, Pilar Galan, Lisette C. De Groot, Jim Halsey, Alan D. Dangour, Rory Collins, and Francine Grodstein

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Practice Patterns and Trends in the Use of Medical Therapy in Patients Undergoing Percutaneous Coronary Intervention in Ontario, Pallav Garg, Harindra C. Wijeysundera, Lingsong Yun, Warren J. Cantor, and Dennis T. Ko

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Localized, Non-Random Differences in Chromatin Accessibility Between Homologous Metaphase Chromosomes, Wahab A Khan, Peter K Rogan, and Joan H.M. Knoll

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Identifying which patients with asymptomatic carotid stenosis could benefit from intervention, Kosmas I. Paraskevas, J. David Spence, Frank J. Veith, and Andrew N. Nicolaides

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Arterial age as a substitute for chronological age in the AGLA risk function could improve coronary risk prediction, Michel Romanens, Franz Ackermann, Isabella Sudano, Thomas Szucs, and J. David Spence

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Asymptomatic carotid stenosis identifying patients at high enough risk to warrant endarterectomy or stenting, J. David Spence, David Pelz, and Frank J. Veith

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Pioglitazone for secondary prevention after ischemic stroke and transient ischemic attack: Rationale and design of the Insulin Resistance Intervention after Stroke Trial, Catherine M. Viscoli, Lawrence M. Brass, Antonio Carolei, Robin Conwit, Gary A. Ford, Karen L. Furie, Mark Gorman, Peter D. Guarino, Silvio E. Inzucchi, Anne M. Lovejoy, Mark W. Parsons, Peter N. Peduzzi, Peter A. Ringleb, Gregory G. Schwartz, J. David Spence, David Tanne, Lawrence H. Young, and Walter N. Kernan

Submissions from 2013

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Why calls for more routine carotid stenting are currently inappropriate: An international, multispecialty, expert review and position statement, Anne L. Abbott, Mark A. Adelman, Andrei V. Alexandrov, P. Alan Barber, Henry J.M. Barnett, Jonathan Beard, Peter Bell, Martin Björck, David Blacker, Leo H. Bonati, Martin M. Brown, Clifford J. Buckley, Richard P. Cambria, John E. Castaldo, Anthony J. Comerota, E. Sander Connolly, Ronald L. Dalman, Alun H. Davies, Hans Henning Eckstein, Rishad Faruqi, Thomas E. Feasby, Gustav Fraedrich, Peter Gloviczki, Graeme J. Hankey, Robert E. Harbaugh, Eitan Heldenberg, Michael G. Hennerici, Michael D. Hill, and Timothy J. Kleinig

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Barometer in the storm--carotid artery plaque quantified by three-dimensional ultrasound, Amer M. Johri and J. David Spece

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Diabetes, intracranial stenosis and microemboli in asymptomatic carotid stenosis, Thach D. Lam, Stephanie Lammers, Claudio Munoz, Arturo Tamayo, and J. David Spence

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Ultrasonographic measure of carotid plaque burden, Tatjana Rundek and J. David Spence

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Intensive risk factor control in stroke prevention, J. David Spence

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Trust between specialists and family physicians, J. David Spence

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Retinal vasculature: a window on the brain., J. David Spence and J. Alexander Fraser

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Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: Meta-analyses of data on 50 000 individuals, Stein Emil Vollset, Robert Clarke, Sarah Lewington, Marta Ebbing, Jim Halsey, Eva Lonn, Jane Armitage, Joann E. Manson, Graeme J. Hankey, J. David Spence, Pilar Galan, Kaare H. Bønaa, Rex Jamison, J. Michael Gaziano, Peter Guarino, John A. Baron, Richard F.A. Logan, Edward L. Giovannucci, Martin Den Heijer, Per M. Ueland, Derrick Bennett, Rory Collins, and Richard Peto