Title

Lymphocytes: Antigen-induced Gene Activation

Document Type

Article

Publication Date

2005

URL with Digital Object Identifier

10.1038/npg.els.0004033

Abstract

Lymphocytes are activated upon antigen recognition by their clone-specific surface antigen receptors. Lymphocyte activation includes multiple signalling cascades that converge in the cell nucleus to cause significant changes in the pattern of gene expression that determine the phenotype of activated lymphocytes and ultimately, the type of immune response.

Notes

Published as an article in: Encyclopedia of Life Sciences.