Master of Science
Dr. Donald H Paterson
PURPOSE: The aim of the present study was to assess the internal consistency and stability reliability of flow-mediated dilation (FMD) in the popliteal artery and to investigate the effect of occlusion pressure on the FMD response. METHODS: A series of FMD tests were performed on ten healthy young adult males to assess reliability. Ultrasound-derived artery diameter of the popliteal was measured and FMD was calculated as the percent change in diameter from baseline. RESULTS: FMD measurements for intra- and interday comparisons demonstrated poor reliability (Repeatability 5.62 and 4.82%, Intraclass correlation coefficient [ICC] 0.36 and 0.25, respectively). Repeatability values were as large as the FMD measures themselves for both intra- and interday reliability. CONCLUSION: Popliteal artery FMD has poor reliability for internal consistency and stability reliability. Interpretation of individual or group changes using this technique should be interpreted with caution.
McLay, Kaitlin M., "Reliability of flow-mediated dilation measures in the popliteal artery and implications for use in clinical and research practices" (2012). University of Western Ontario - Electronic Thesis and Dissertation Repository. Paper 831.