Chemistry Publications

Document Type

Article

Publication Date

10-6-2010

Journal

Organic letters

Volume

12

Issue

21

First Page

4732

Last Page

4735

URL with Digital Object Identifier

10.1021/ol102062t

Abstract

A new synthesis of 2-alkoxy-1,1-cyclobutane diesters and their first use in dipolar cycloadditions is reported. Both the formation of the donor-acceptor cyclobutanes and their subsequent annulation with in situ formed imines are catalyzed by Yb(OTf)(3). Cyclobutanes with carbon donor groups give piperidines with high trans stereoselectivity.


Find in your library

Included in

Chemistry Commons

Share

COinS