Chemistry Publications

Document Type

Article

Publication Date

2017

Journal

European Journal of Organic Chemistry

Abstract

Lewis acid promoted cycloaddition reactions of donoracceptor cyclopropanes are one of the well-studied approaches for the construction of heterocyclic and carbocyclic frameworks. During our efforts to exploit this strategy for the synthesis and functionalization of carbohydrate derived systems, we discovered the cycloaddition of nitriles with DA cyclopropanes. This personal account details our contributions to the development of this cycloaddition. The reaction discovery, methods development, and application in total synthesis along with relative examples from others has been discussed.

Notes

accepted for publication

Available for download on Saturday, September 01, 2108


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