Chemistry Publications

Title

Blue Fluorescent Deoxycytidine Analogues: Convergent Synthesis, Solid-state and Electronic Structure, and Solvatochromism

Document Type

Article

Publication Date

2-7-2010

Journal

Organic & Biomolecular Chemistry

Volume

8

Issue

3

First Page

663

Last Page

666

URL with Digital Object Identifier

http://dx.doi.org/10.1039/b919921g

Abstract

We report the synthesis and photospectroscopic characterisation of intrinsically fluorescent triazole-appended cytidines. Fluorescence was found to be highly dependent on solvent conditions. X-Ray crystallographic data show the proton of the exocyclic amine of the nucleobase and the triazole N(3) engaged in a H-bond.