This collection contains theses and dissertations from the Department of Biomedical Engineering, collected from the Scholarship@Western Electronic Thesis and Dissertation Repository

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Theses/Dissertations from 2024

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Co-delivery of Adipose-derived Stromal Cells and Endothelial Colony Forming Cells in Novel Cell-assembled Scaffolds as a Pro-angiogenic Cell Therapy Platform, Sarah A. From

Theses/Dissertations from 2023

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Multiparametric Classification of Tumor Treatment Using Ultrasound Microvascular Imaging, mahsa bataghva

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Towards Patient Specific Mitral Valve Modelling via Dynamic 3D Transesophageal Echocardiography, Patrick Carnahan

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Developing a Finite Element Model for Evaluating the Posterior Tibial Slope in a Medial Opening Wedge High Tibial Osteotomy, VIctor Alexander Carranza

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Analysis and Characterization of Embroidered Textile Strain Sensors for Use in Wearable Mechatronic Devices, Jose Guillermo Colli Alfaro

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Developing Bioactive Hydrogels Containing Cell-derived Extracellular Matrix for Bone and Cartilage Repair, Ali Coyle

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Modelling of a TCA-driven Wearable Tremor Suppression Device for People with Parkinson’s Disease, Parisa Daemi

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Using Machine Learning Models to Address Challenges in Lung Cancer Care, Salma Dammak

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Longitudinal dynamics of cerebrospinal fluid Aꞵ, pTau and sTREM2 reveal predictive preclinical trajectories of Alzheimer’s pathology, Bahaaldin Helal

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MAGNETIC RESONANCE IMAGING BIOMARKERS FOR PARKINSON’S DISEASE: A MACHINE LEARNING APPROACH, Dimuthu Henadeerage Don

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Detecting Treatment Failure in Rheumatoid Arthritis with Time-Domain Diffuse Optical Methods, Seva Ioussoufovitch

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Novel Magnetic Resonance Imaging-Compatible Mechatronic Needle Guidance System for Prostate Focal Laser Ablation Therapy, Eric R. Knull

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The Development of Stimuli-responsive Hydrogels from Self-Immolative Polymers, Jared David Pardy

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Free-hand Photoacoustic Imaging of Breast Cancer Tissue, Elina Rascevska

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Development of a Cell-based Regenerative Strategy to Modulate Angiogenesis and Inflammation in Ischemic Muscle, Fiona E. Serack

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Investigation of Dynamic Culture on Matrix-derived Microcarriers as a Strategy to Modulate the Pro-Regenerative Phenotype of Human Adipose-derived Stromal Cells, McKenna R. Tosh

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Evaluating EEG–EMG Fusion-Based Classification as a Method for Improving Control of Wearable Robotic Devices for Upper-Limb Rehabilitation, Jacob G. Tryon

Theses/Dissertations from 2022

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A two-layer continuous-capillary oxygen transport model: Development and application to blood flow regulation in resting skeletal muscle., Keith C. Afas

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Development of a Hybrid Stereotactic Guidance System For Percutaneous Liver Tumour Ablation, Joeana N. Cambranis Romero

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Large-scale Analysis and Automated Detection of Trunnion Corrosion on Hip Arthroplasty Devices, Anastasia M. Codirenzi

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The Role of Transient Vibration of the Skull on Concussion, Rodrigo Dalvit Carvalho da Silva

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Biomechanical Investigation of Complete and Partial Medial Collateral Ligament Injuries, Callahan Doughty

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Towards A Comprehensive Software Suite for Stereotactic Neurosurgery, Greydon Gilmore

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The Bio-Mechanical Development and Kinematic Evaluation of Zone I and Zone II Injuries and their Corresponding Surgical Repair Techniques using an In-Vitro Active Finger Motion Simulator: A Cadaveric Study, Mohammad Haddara

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Image-based Cochlear Implant Frequency-to-Place Mapping, Luke William Helpard

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Mechanical Evaluation of Gyroid Structures to Combat Orthopaedic Implant Infections, Sydney Hitchon

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The Development of a Motion Sensing Device for Use in a Home Setting, Jaspreet K. Kalsi

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A Novel Ultrasound Elastography Technique for Evaluating Tumor Response to Neoadjuvant Chemotherapy in Patients with Locally Advanced Breast Cancer, Niusha Kheirkhah

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Thermo-responsive Antibiotic-Eluting Coatings for Treating Infection near Orthopedic Implants, Jan Chung Kwan

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Effects of Modulating the Culture Microenvironment on the Growth and Secretome of Human Adipose-Derived Stromal Cells, Zhiyu Liang

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Conducting Polypyrrole Hydrogel Biomaterials For Drug Delivery And Cartilage Tissue Regeneration, Iryna Liubchak

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Motion and Crosslinked Polyethylene Wear in Reverse Total Shoulder Arthroplasty, Christopher Millward

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Intracardiac Ultrasound Guided Systems for Transcatheter Cardiac Interventions, Hareem Nisar

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Investigation of Cell Derived Nanoparticles for Drug Delivery and Osteogenic Differentiation of Human Stem/Stromal Cells, Shruthi Polla Ravi

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Quantitative Image Analysis of White Matter Dysregulation Using Brain Normalization for Diagnostic Analysis of Pediatric Hydrocephalus, Renee-Marie Ragguett

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Automation through Deep-Learning to Quantify Ventilation Defects in Lungs from High-Resolution Isotropic Hyperpolarized 129Xe Magnetic Resonance Imaging, Tuneesh Kaur Ranota

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Early Biological Response of Articular Cartilage to Hemiarthroplasty Wear, Debora Rossetti

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Sol-Gel Derived Bioceramic Poly(Diethyl Fumarate – Co – Triethoxyvinylsilane) Composite, Aref Sleiman

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The Application of Digital Volume Correlation Bone Strain Measurements in the Osteoarthritic Glenohumeral Joint, Jakub R. Targosinski

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Development of Brain-Derived Bioscaffolds for Neural Progenitor Cell Culture and Delivery, Julia Terek

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Modelling and Evaluation of Piezoelectric Actuators for Wearable Neck Rehabilitation Devices, Shaemus D. Tracey

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Development of a Combined Experimental-Computational Framework to Study Human Knee Biomechanics, Samira Vakili

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Investigation on the Performance of Dry Powder Inhalation System for Enhanced Delivery of Levosalbutamol Sulfate, Yuqing Ye

Theses/Dissertations from 2021

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Development of a Wireless Telemetry Load and Displacement Sensor for Orthopaedic Applications, William Anderson

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Organic-Inorganic Hybrid Biomaterials for Bone Tissue Engineering and Drug Delivery, Neda Aslankoohi

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Fabrication Of Inkjet-Printed Enzyme-Based Biosensors Towards Point-Of-Care Applications, Yang Bai

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The Use of CT to Assess Shoulder Kinematics and Measure Glenohumeral Arthrokinematics, Baraa Daher

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The Development of Region-Specific Decellularized Meniscus Bioinks for 3D Bioprinting Applications, Sheradan Doherty

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In Vitro Analyses of the Contributions of the Hip Capsule to Joint Biomechanics, Emma Donnelly

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Long-Circulating, Degradable Lanthanide-Based Contrast Agents for Pre-Clinical Microcomputed Tomography of the Vasculature, Eric Grolman

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Mixed-reality visualization environments to facilitate ultrasound-guided vascular access, Leah Groves

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Diffusion Kurtosis Imaging in Temporal Lobe Epilepsy, Loxlan W. Kasa

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Extracellular Matrix-Derived Microcarriers as 3-D Cell Culture Platforms, Anna Kornmuller

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3D Printed Polypyrrole Scaffolds for pH Dependent Drug Delivery with Applications in Bone Regeneration, Matthew T. Lawrence

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Development of Multifunctional Drug Delivery Systems for Locoregional Therapy, Xinyi Li

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Motion Intention Estimation using sEMG-ACC Sensor Fusion, Jose Alejandro Lopez

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Biomaterial for Cervical Intervertebral Disc Prosthesis, Helium Mak

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Biomechanical Analysis of Ligament Modelling Techniques and Femoral Component Malrotation Following TKA, Liam A. Montgomery

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Snapshot Three-Dimensional Surface Imaging With Multispectral Fringe Projection Profilometry, Parsa Omidi

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4DCT to Examine Carpal Motion, Sydney M. Robinson

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Seizure Detection Using Deep Learning, Information Theoretic Measures and Factor Graphs, Bahareh Salafian

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Modeling Fetal Brain Development: A semi-automated platform for localization, reconstruction, and segmentation of the fetal brain on MRI, Jianan Wang

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Immobilized Jagged1 for Notch3-specific Differentiation and Phenotype Control of Vascular Smooth Muscle Cells, Kathleen E. Zohorsky

Theses/Dissertations from 2020

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Simulation Approaches to X-ray C-Arm-based Interventions, Daniel R. Allen

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Implementing a multi-segment foot model in a clinical setting to measure inter-segmental joint motions, Tahereh Amiri

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Cardiac Modelling Techniques to Predict Future Heart Function and New Biomarkers in Acute Myocardial Infarction, Sergio C. H. Dempsey

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Feasibility of Twisted Coiled Polymer Actuators for Use in Upper Limb Wearable Rehabilitation Devices, Brandon P.R. Edmonds

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Metal Additive Manufacturing for Fixed Dental Prostheses, Mai EL Najjar

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Using an Internal Auditory Stimulus to Activate the Developing Primary Auditory Cortex: A Fetal fMRI Study, Estee Goldberg

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Development of Water-Soluble Polyesters for Tissue Engineering Applications, Trent Gordon

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Development Of Hybrid Coating Materials To Improve The Success Of Titanium Implants, Zach Gouveia

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A 3D Printed Axon-Mimetic Diffusion MRI Phantom, Tristan K. Kuehn

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Development of an Active Infection Monitoring Knee Spacer for Two-Stage Revision, Michael K. Lavdas

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Computational Modeling of the Human Brain for mTBI Prediction and Diagnosis, Yanir Levy

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Pulmonary Imaging of Chronic Obstructive Pulmonary Disease using Multi-Parametric Response Maps, Jonathan MacNeil

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Optimization of Indentation for the Material Characterization of Soft PVA-Cryogels, Md. Mansur ul Mulk

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Development and Validation of Augmented Reality Training Simulator for Ultrasound Guided Percutaneous Renal Access, Yanyu Mu

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A Biomechanical Investigation into the Effect of Experimental Design on Wrist Biomechanics and Contact Mechanics, Clare E. Padmore

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Structure-Function Relationships in the Brain: Applications in Neurosurgery, Daiana-Roxana Pur

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The Effect of Joint Alignment After a Wrist Injury on Joint Mechanics and Osteoarthritis Development, Puneet Kaur Ranota

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Development and Validation of Tools for Improving Intraoperative Implant Assessment with Ultrasound during Gynaecological Brachytherapy, Jessica Robin Rodgers

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Studies on Carbon Quantum Dots with Special Luminescent Properties and Their Capability of Overcoming the Biological Barriers, Ji Su Song

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Machine Learning towards General Medical Image Segmentation, Clara Tam

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The Migration and Wear of Reverse Total Shoulder Arthroplasty, Madeleine L. Van de Kleut

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Video Processing for the Evaluation of Vascular Dynamics in Neurovascular Interventions, Reid Vassallo

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Preparation of Intra-articular Drug Delivery Systems for the Treatment of Osteoarthritis, Ian Villamagna

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Deep Reinforcement Learning in Medical Object Detection and Segmentation, Dong Zhang

Theses/Dissertations from 2019

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Fabrication and Characterization of Collagen-Polypyrrole Constructs Using Direct-Ink Write Additive Manufacturing, Rooshan Arshad

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Development of a Force-Based Ream Vector Measurement System For Glenoid Reaming Simulation, David Axford

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Investigation of Visual Perceptions in Parkinson's Disease and the Development of Disease Monitoring Software, Matthew Bernardinis

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Tissue Equivalent Gellan Gum Gel Materials for Clinical MRI and Radiation Dosimetry, Pawel Brzozowski

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Implementation of User-Independent Hand Gesture Recognition Classification Models Using IMU and EMG-based Sensor Fusion Techniques, José Guillermo Collí Alfaro

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Scaffold Design Considerations for Soft Tissue Regeneration, Madeleine M. Di Gregorio

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Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters, Daniel Gelman

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High-throughput Fabrication of Drug-loaded Core-shell Tablets with Adjustable Release Profiles from Surface-erodible and Photocrosslinkable Polyanhydrides, Armin Geraili Nejadfomeshi

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Apply dry powder on drug loading and enteric coating of esomeprazole magnesium trihydrate beads and capsules, Xiaojing Ge

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Bioluminescence resonance energy transfer (BRET) - based nanostructured biosensor for detection of glucose, Eugene Hwang

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A Heterogeneous Patient-Specific Biomechanical Model of the Lung for Tumor Motion Compensation and Effective Lung Radiation Therapy Planning, Parya Jafari

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The Co-Delivery of Syngeneic Adipose-Derived Stromal Cells and Macrophages on Decellularized Adipose Tissue Bioscaffolds for In Vivo Soft Tissue Regeneration, Hisham A. Kamoun

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Improving Material Mapping in Glenohumeral Finite Element Models: A Multi-Level Evaluation, Nikolas K. Knowles